KEY PUBLICATIONS2020-09-05T10:18:50+02:00
MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset.2023-12-12T12:37:38+01:00

Thomalla, G., Simonsen, C. Z., Boutitie, F., Andersen, G., Berthezene, Y., Cheng, B., Cheripelli, B., Cho, T.-H., Fazekas, F., Fiehler, J., Ford, I., Galinovic, I., Gellissen, S., Golsari, A., Gregori, J., Günther, M., Guibernau, J., Häusler, K. G., Hennerici, M., Kemmling, A., Marstrand, J., Modrau, B., Neeb, L., Perez de la Ossa, N., Puig, J., Ringleb, P., Roy, P., Scheel, E., Schonewille, W., Serena, J., Sunaert, S., Villringer, K., Wouters, A., Thijs, V., Ebinger, M., Endres, M., Fiebach, J. B., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S. & Gerloff, C.

MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. 

New Engl. J. Med. 379, 611–622 (2018)

10.1056/NEJMoa1804355

Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke.2023-12-12T12:35:47+01:00

Schlemm E, Ingwersen T, Königsberg A, Boutitie F, Ebinger M, Endres M, Fiebach J, Fiehler J, Galinovic I, Lemmens R, Muir Keith, Nighoghossian N, Pedraza S, Puig J, Simonsen C, Thijs V, Wouters A, Gerloff C, Thomalla, Cheng B

Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke. 2021

Nat. Commun. 2021;12:2590.

https://doi.org/10.1038/s41467-021-22786-w

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.2023-12-12T12:37:00+01:00

Thomalla G, Boutitie F, Ma H, Koga M, Ringleb P, Schwamm LH, Wu O, Bendszus M, Bladin CF, Campbell B, Cheng B, Churilov L, Ebinger M, Endres M, Fiebach JB, Fukuda-Doi M, Inoue M, Kleinig TJ, Latour LL, Lemmens R, Levi C, Leys D, Miwa K, Molina CA, Muir KW, Nighoghossian N, Parsons MW, Pedraza S, Schellinger PD, Schwab S, Simonsen CZ, Song SS, Thijs V, Toni C, Hsu CY, Wahlgren N, Yamamoto H, Yassi N, Yoshimura S, Warach S, Hacke W, Toyoda K, Donnan GA, Davis SM,  Gerloff C, on behalf of the Evaluation of unknown Onset Stroke thrombolysis trials (EOS) investigators

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.

Lancet 2020; 396: 1574–1584.

10.1016/S0140-6736(20)32163-2

Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial2023-12-12T12:36:38+01:00

Martin Bendszus, Jens Fiehler, Fabien Subtil, Susanne Bonekamp, Anne Hege Aamodt, Blanca Fuentes, Elke R Gizewski, Michael D Hill, Antonin Krajina, Laurent Pierot, Claus Z Simonsen, Kamil Zeleňák, Rolf A Blauenfeldt, Bastian Cheng, Angélique Denis, Hannes Deutschmann, Franziska Dorn, Fabian Flottmann, Susanne Gellißen, Johannes C Gerber, Mayank Goyal, Jozef Haring, Christian Herweh, Silke Hopf-Jensen, Vi Tuan Hua, Märit Jensen, Andreas Kastrup, Christiane Fee Keil, Andrej Klepanec, Egon Kurča, Ronni Mikkelsen, Markus Möhlenbruch, Stefan Müller-Hülsbeck, Nico Münnich, Paolo Pagano, Panagiotis Papanagiotou, Gabor C Petzold, Mirko Pham, Volker Puetz, Jan Raupach, Gernot Reimann, Peter Arthur Ringleb, Maximilian Schell, Eckhard Schlemm, Silvia Schönenberger, Bjørn Tennøe, Christian Ulfert, Kateřina Vališ, Eva Vítková, Dominik F Vollherbst, Wolfgang Wick, Götz Thomalla, on behalf of the TENSION Investigators

Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial.

Lancet. 2023;402:1753–1763.

10.1016/S0140-6736(23)02032-9

 

Influence of Stroke Infarct Location on Functional Outcome Measured by the Modified Rankin Scale2023-12-12T12:38:20+01:00

Cheng, B., Forkert, N. D., Zavaglia, M., Hilgetag, C. C., Golsari, A., Siemonsen, S., Fiehler, J., Pedraza, S., Puig, J., Cho, T., Alawneh, J., Baron, J., Ostergaard, L., Gerloff, C. & Thomalla, G.

Influence of Stroke Infarct Location on Functional Outcome Measured by the Modified Rankin Scale.

Stroke 45, 1695–1702 (2014).

https://doi.org/10.1161/STROKEAHA.114.005152

Mapping the deficit dimension structure of the National Institutes of Health Stroke Scale.2023-12-12T12:35:11+01:00

Cheng B, Chen J, Königsberg A, Mayer C, Rimmele L, Patil KR, Gerloff C, Thomalla G, Eickhoff SB.

Mapping the deficit dimension structure of the National Institutes of Health Stroke Scale.

eBioMedicine. 2023;87:104425.

doi: 10.1016/j.ebiom.2022.104425

 

Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment2020-09-07T15:13:17+02:00

Alegiani, A. C., Dorn, F., Herzberg, M., Wollenweber, F. A., Kellert, L., Siebert, E., Nolte, C. H., von Rennenberg, R., Hattingen, E., Petzold, G. C., Bode, F. J., Pfeilschifter, W., Schäfer, J. H., Wagner, M., Röther, J., Eckert, B., Kraft, P., Pham, M., Boeckh-Behrens, T., Wunderlich, S., Bernkopf, K., Reich, A., Wiesmann, M., Mpotsaris, A., Psychogios, M., Liman, J., Maier, I., Berrouschot, J., Bormann, A., Limmroth, V., Spreer, J., Petersen, M., Krause, L., Lowens, S., Kraemer, C., Zweynert, S., Lange, K. S., Thonke, S., Kastrup, A., Papanagiotou, P., Alber, B., Braun, M., Fiehler, J., Gerloff, C., Dichgans, M. & Thomalla, G.

Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment.

Int. J. Stroke 14, 372–380 (2019).

Functional Outcome of Intravenous Thrombolysis in Patients with Lacunar Infarcts in the WAKE-UP Trial2020-09-07T15:14:23+02:00

Barow, E., Boutitie, F., Cheng, B., Cho, T. H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Nickel, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C. & Thomalla, G.

Functional Outcome of Intravenous Thrombolysis in Patients with Lacunar Infarcts in the WAKE-UP Trial.

JAMA Neurol. 76, 641–649 (2019).

Early rhythm-control therapy for atrial fibrillation in patients with a history of stroke: a subgroup analysis of the EAST-AFNET 4 trial2023-12-12T12:36:13+01:00

Jensen M, Suling A, Metzner A, Schnabel RB, Borof K, Goette A, Haeusler KG, Zapf A, Wegscheider K, Fabritz L, Diener HC, Thomalla G, Kirchhof P

Early rhythm-control therapy for atrial fibrillation in patients with a history of stroke: a subgroup analysis of the EAST-AFNET 4 trial.

Lancet Neurology 22, 45-54 (2023).

https://doi.org/10.1016/S1474-4422(22)00436-7

Structural brain networks and functional motor outcome after stroke—a prospective cohort study2020-09-07T15:13:59+02:00

Schlemm, E., Schulz, R., Bönstrup, M., Krawinkel, L., Fiehler, J., Gerloff, C., Thomalla, G. & Cheng, B.

Structural brain networks and functional motor outcome after stroke—a prospective cohort study.

Brain Commun. 2, (2020).

Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection2023-12-12T12:39:11+01:00

Marvin Petersen, Felix Leonard Nägele, Carola Mayer, Maximilian Schell , Elina Petersen , Simone Kühn, Jürgen Gallinat Jens Fiehler, Ofer Pasternak, Jakob Matschke, Markus Glatzel, Raphael Twerenbold, Christian Gerloff, Götz Thomalla, and Bastian Cheng

Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection.

Proc. Natl. Acad. Sci. 2023;120:2017.

https://doi.org/10.1073/pnas.2217232120

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